Enzymes catalyze reaction by stabilizing the _____. If the enzyme binds to the substrate too well, the activation energy for the catalyzed reaction _. Thus, the enzyme binds best to the _, and the activation energy _____.

Most of the chemical reactions are slow because of the transition state barriers. It requires a lot of energy to cross the transition state barriers. So enzymes provide an alternate pathway for carrying out the reaction by stabilizing the transition state. When enzymes interact with the substrates with the help of functional groups present in their active sites it results in the lowering of activation energy because the transition state gets stabilized with the help of enzyme.

Enzymes catalyze reaction by stabilizing the _________. If the enzyme binds to the substrate too well, the activation energy for the catalyzed reaction _________. Thus, the enzyme binds best to the _________, and the activation energy _________.

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Enzymes catalyze reaction by stabilizing the _____. If the enzyme binds to the substrate too well, the activation energy for the catalyzed reaction _. Thus, the enzyme binds best to the _, and the activation energy _____.