Respuesta :
Sequential cleavage from the non-reducing terminals of glucose molecules is required for both glycogen degradation and polysaccharides hydrolysis.
Why non-reducing end is selected for digestion?
A polysaccharide's non-reducing end is the one where an anomeric carbon participates in the glycosidic connection. The elimination of carbohydrate remnants one at a time out from the non-reducing terminal occurs during glycogenolysis and polysaccharides hydrolysis.
- For example, several enzymes are involved in glycogenolysis in the liver and muscle.
- An example of such an enzyme is glycogen phosphorylase, which catalyzes the successive dissociation of the alpha 1->4 glycosidic bond that connects two glucose molecules at a non-reducing terminal of glycogen. The last glucose residue is eliminated as alpha-D-glucose 1-phosphate.
That is why non-reducing end of glucose is chosen for digestion or breakdown of the carbohydrate polymer.
Learn more about non-reducing here:
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