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The range for the target ph of a buffer solution that would favours ph stabilization unders this condition in (4.75-4.85).
What is Henderson Hasselback equation ?
The Henderson-Hasselbalch equation, pH = pKa + log([A]/[HA]), can be used to determine the pH of a buffer. The terms "HA" and "A" in this equation stand for the equilibrium concentrations of the conjugate acid-base pair that were employed to make the buffer solution.
What is acetate?
A proton is taken out of the carboxy group of acetic acid to produce acetate, a monocarboxylic acid anion. It performs a function as a Saccharomyces cerevisiae metabolite as well as a human metabolite. The base is a conjugate of an acetic acid. ChEBI. Alternatives to ACETIC ACID
The Henderson Hasselback equation for a suitable acetic acid / acetate buffer-
Ph= Pka + log (salt)/(acid)
(salt) = (acetate)
(acid) = (acetic acid)
now, CH3 COOH dissociates as
CH3COOH ⇔ CH3COOH +H
Pka for CH3COOH = 4.75
If a chemical reaction produced hydroxide ions, then CH3COOH gets consumed and more acetate ions with produces. This leads to change in Ph of the solution as due (CH3C00H-) increases the ph absence increases.
The range for the target ph of a buffer solution that would favours ph stabilization unders this condition in (4.75-4.85)
The buffer capacity is the ability of a given buffer to resist any changes in ph when small amount of acid or base added to it.The buffer capacity of a mixed weak acid( here Acetic acid)-base (NaOH) buffer is much greater when the individual pKa values are in close proximity with each other.
Therefore, The range for the target ph of a buffer solution that would favours ph stabilization unders this condition in (4.75-4.85).
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